Rhiana C Simon, PhD

A.P. Giannini Postdoctoral Scholar at UCSF
Systems neuroscience & neurodevelopment

I am currently a postdoc at UCSF, where I examine how opioid exposure and withdrawal during critical periods in neurodevelopment alter long-term gene expression programs in the septum.My goal is to develop a research program that will critically dissect the role for endogenous opioid signaling in neurodevelopment. I am also interested in examining how early life insults (e.g. adversity, malnutrition, drug exposure) cause long-lasting alterations in adult neurocircuitry and motivated behavior.

[1]
Combining transcriptomics with viral toolkits to interrogate neurocircuitry underlying motivated and innate behavior

[2]
Examining how opioid use disorder disrupts the molecular and functional organization of limbic neurocircuitry

[3]
Assessing the impact of developmental opioid exposure on the production, maturation, and integration of limbic neurons